NCBI
National Center for
Biotechnology Information
Search
1W51:
BACE (Beta Secretase) in complex with a nanomolar non-peptidic inhibitor
PDB ID:
1W51
Download
MMDB ID:
29721
PDB Deposition Date:
2004/8/4
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.55 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1W51: monomeric; determined by author and by software (PQS)
Molecular Components in 1W51
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemicals and Non-standard biopolymers (5 molecules)
1
4
IODIDE ION
2
1
3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)(HYDROXY)METHYL]-N,N-DIPROPYLBENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303